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Page: Contraindications
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The WHO Medical Eligibility Criteria for Contraceptive Use and RCOG Faculty of Family Planning & Reproductive Health Care (FFPRHC) UK Medical Eligibility Criteria for Contraceptive Use list the following as conditions where use of Depo-Provera is not usually recommended or should not be used because of an unacceptable health risk or because it is not indicated:
Conditions where the theoretical or proven risks usually outweigh the advantages of using Depo-Provera:
* Multiple risk factors for arterial cardiovascular disease
* Current deep vein thrombosis (DVT) or pulmonary embolus (PE)
* Migraine headache with aura while using Depo-Provera
* Before evaluation of unexplained vaginal bleeding suspected of being a serious condition
* Past history of breast cancer and no evidence of current disease for 5 years
* Active liver disease: (acute viral hepatitis, severe decompensated cirrhosis, benign or malignant liver tumours)
* Conditions of concern for hypo-estrogenic effects and reduced HDL levels theoretically increasing cardiovascular risk:
o Hypertension with vascular disease
o Current and history of ischemic heart disease
o History of stroke
o Diabetes for > 20 years or with nephropathy/retinopathy/neuropathy or vascular disease
Conditions which represent an unacceptable health risk if Depo-Provera is used:
* Current or recent breast cancer (a hormonally sensitive tumour)
Conditions where use of Depo-Provera is not indicated and should not be initiated:
* Pregnancy
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Important notice:
The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other
qualified health provider with any questions you may have regarding a medical condition.
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