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The main pharmacological effects of digoxin are on the heart. Extracardiac effects are responsible for many of the adverse effects (see below).

Its main cardiac effects are

* A decrease of conduction of electrical impulses through the AV node, making it a commonly used drug in controlling the heart rate during atrial fibrillation or atrial flutter.
* An increase of force of contraction via inhibition of the Na+/K+ ATPase pump (see below).

Digoxin
This drug is used to treat heart failure. This article profiles the medication and its side effects.

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