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The diagnosis is visual; very few other diseases mimic herpes zoster, especially in the localization of the rash, which is otherwise quite similar in appearance and initial effect to that of poison oak or poison ivy. In case of doubt, herpes tests can be performed where fluid from a blister may be taken so the cells can be analyzed in a medical laboratory. Herpes test are among many possible forms of testing for the disease. Physicians can take a viral culture of the skin, which involves a microscopic examination of the skin using a Tzanck preparation. While looking at the cell obtained from the blister, the cells infected with the herpes virus will appear very large and contain many dark nuclei. By taking a complete blood count there may be an elevated number of white blood cells, which is an indirect sign of infection. There may also be a rise in the antibody to the virus that will give indication of the virus’ reactivation as well. Lab tests are necessary because, depending on the affected sensory nerve, the pain that is experienced before the onset of the rash may be misdiagnosed as pleurisy, myocardial infarction, appendicitis, cholelithiasis, or a migraine headache.
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Important notice:
The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other
qualified health provider with any questions you may have regarding a medical condition.
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