Adverse Effects

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Adverse Effects


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Possible adverse drug reactions include:

* Hypotension, especially if the dosage is too high.
* Arrhythmias, although these are uncommon.
* Nausea, which is often helped by taking the drug with food, although protein interferes with drug absorption.
* Gastrointestinal bleeding.
* Disturbed respiration. This is not always harmful, and can actually benefit patients with upper airway obstruction.
* Hair loss.
* Confusion.
* Extreme emotional states, particularly anxiety, but also excessive libido.
* Vivid dreams and/or fragmented sleep.
* Visual and possibly auditory hallucinations.
* Effects on learning. There is some evidence that it improves working memory, while impairing other complex functions.
* Sleepiness and sleep attacks.
* a condition similar to amphetamine psychosis.

Although there are a number of adverse effects associated with levodopa, particularly psychiatric ones, it has fewer than other anti-Parkinson's drugs, including anticholinergics, amantadine, and dopamine agonists.

More serious are the effects of chronic levodopa administration, which include:

* End-of-dose deterioration of function.
* On/off oscillations.
* Freezing during movement.
* Dose failure (drug resistance).
* Dyskinesia at peak dose.

Clinicians will try to avoid these by limiting levodopa dosages as far as possible until absolutely necessary.

Levodopa
This drug is used to treat Parkinson's disease. This article profiles the medication, how it works, and possible side effects.

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