Uses

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Uses


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Breast cancer treatment

It is used for the treatment of early and advanced estrogen receptor (ER) positive breast cancer in pre- and post-menopausal women. It is also approved by the Food and Drug Administration (FDA) for the reduction of the incidence of breast cancer in women at high risk of developing the disease. It has been further approved for the reduction of contralateral (in the opposite breast) breast cancer.

Nolvadex was first approved by the FDA on December 30, 1977 for treatment of metastatic breast cancer. It is also available as a generic drug in a number of countries.

On April 17, 2006, it was announced that raloxifene is equally effective in reducing the incidence of breast cancer, but caused fewer side effects.

Other uses

A rare condition occasionally treated with tamoxifen is retroperitoneal fibrosis.

Tamoxifen is sometimes used to treat gynecomastia in men. Tamoxifen is also used by bodybuilders in a steroid cycle to try and prevent or reduce drug-induced gynecomastia caused by steroids that are used in the same cycle.

Tamoxifen is also used to treat infertility in women with anovulatory disorders. A dose of 10-40 mg per day is administered in days 3-7 of a woman's cycle.

Tamoxifen
This drug is used in the treatment of breast cancer and endometrial cancer, but it can have significant side effects. This article profiles these and how the medicine works.

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