Genetics

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Genetics

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Familial melanoma is genetically heterogeneous, and loci for familial melanoma have been identified on the chromosome arms 1p, 9p and 12q. Multiple genetic events have been related to the pathogenesis of melanoma. The multiple tumor suppressor 1 (CDKN2A/MTS1) gene encodes p16INK4a - a low-molecular weight protein inhibitor of cyclin-dependent protein kinases (CDKs) - which has been localised to the p21 region of human chromosome 9.

Melanoma
Melanoma is the most serious form of skin cancer. This article looks at suspicious spots and surgery to remove them.

• Cancer - Melanoma...
• Cancer - History...
• Cancer - Epidemiology and Causes...
• Cancer - Genetics...
• Cancer - PreventionMinimizing exposure to sources of ultraviolet radiation (the sun and sunbeds),[23] followi...
• Cancer - Diagnosis...
• Cancer - Types of Primary Melanoma...
• Cancer - Prognostic Factors...
• Cancer - Staging...
• Cancer - Treatment...



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