Metabolism and Excretion

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Omeprazole is completely metabolised by the cytochrome P450 system, mainly in the liver. Identified metabolites are the sulphone, the sulphide and hydroxy-omeprazole, which exert no significant effect on the acid secretion. About 80% of an orally given dose is excreted as metabolites in the urine and the remainder is found in the feces, primarily originating from bile secretion.

Omeprazole
Losec is a drug used to treat stomach ulcers and gastric reflux. This article profiles the medication and its side effects.

• Bowel and Abdominal Problems - Omeprazole...
• Bowel and Abdominal Problems - Clinical use...
• Bowel and Abdominal Problems - Dosage Forms...
• Bowel and Abdominal Problems - Absorption and Distribution...
• Bowel and Abdominal Problems - Metabolism and Excretion...

Home > Bowel and Abdominal Problems > Metabolism and Excretion

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