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Page: Acid Reflux and Esophageal Cancer
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The infection rate with H. pylori has been decreasing in developing countries, presumably because of improved hygiene and increased use of antibiotics. Accordingly, the incidence of gastric cancer in the U.S. has fallen by 80 percent from 1900 to 2000. However, gastroesophageal reflux disease and esophageal cancer have increased dramatically during the same period. In 1996, Martin J. Blaser put forward the theory that H. pylori might also have a beneficial effect: by regulating the acidity of the stomach contents, it lowers the impact of regurgitation of stomach acids into the esophagus. While some favorable evidence has been accumulated, as of 2005 the theory is not universally accepted.
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