Signs and Symptoms

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Signs and Symptoms


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Abnormalities include:

* neutropenia, anemia and thrombocytopenia (low cell counts of white and red blood cells, and platelets, respectively)
* abnormal granules in cells, abnormal nuclear shape and size
* chromosomal abnormalities, including chromosomal translocations and abnormal chromosome number.

Symptoms of myelodysplastic conditions:

* Anemia—chronic tiredness, shortness of breath, chilled sensation, sometimes chest pain
* Neutropenia (low neutrophil count) —increased susceptibility to infection
* Thrombocytopenia (low platelet count) —increased susceptibility to bleeding

Although there is some risk for developing acute myelogenous leukemia, about 50% of deaths occur as a result of bleeding or infection. Leukemia that occurs as a result of myelodysplasia is notoriously resistant to treatment.

Myelodysplastic Syndrome
This is a blood disorder caused by changes in the bone marrow. It mainly affects people over the age of 50. This article discusses the symptoms and management of the syndrome.

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